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Comment: Differential Expression Genes as Independent Variables
by
Gordon Smyth
52k
Such an analysis cannot be done in limma. Sorry, I cannot tell you how to do it or even whether it is possible.
Comment: Differential Expression Genes as Independent Variables
by
abadgerw
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The data that is repeated is a quantitative metric of post-mortem pathology across multiple sections. Not all patients have the same number…
Answer: Crossover design with limma
by
Gordon Smyth
52k
Your experiment is somewhat more elaborate than a classical crossover design because of the period-specific baseline controls. The analyses…
Answer: Differential Expression Genes as Independent Variables
by
Gordon Smyth
52k
Sorry, your question doesn't make sense to me. There are tens of thousands of genes and you can't run a mixed model analysis with one depen…
Comment: What type of counts data to import for performing Isoform analysis in edgeR
by
Gordon Smyth
52k
ATPoint and I have both already told you that you cannot use any of the output files from nf-core, and why that is so. I explained to you t…
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